Glyco-engineering strategies for the development of therapeutic enzymes with improved efficacy for the treatment of lysosomal storage diseases

Lysosomal storage diseases (LSDs) are a group of inherent diseases characterized by massive accumulation of undigested compounds in lysosomes, which is caused by genetic defects resulting in the deficiency of a lysosomal hydrolase. Currently, enzyme replacement therapy has been successfully used for...

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Bibliographic Details
Published in:BMB Rep
Main Author: Oh, Doo-Byoung
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2015
Subjects:
Invited Mini Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576951/
https://ncbi.nlm.nih.gov/pubmed/25999178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.8.101
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