Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders

In the present study the use of extracellular vesicles (EVs) as vehicles for therapeutic enzymes in lysosomal storage disorders was explored. EVs were isolated from mammalian cells overexpressing alpha‐galactosidase A (GLA) or N‐sulfoglucosamine sulfohydrolase (SGSH) enzymes, defective in Fabry and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Seras‐Franzoso, Joaquin, Díaz‐Riascos, Zamira V., Corchero, José Luis, González, Patricia, García‐Aranda, Natalia, Mandaña, Mònica, Riera, Roger, Boullosa, Ana, Mancilla, Sandra, Grayston, Alba, Moltó‐Abad, Marc, Garcia‐Fruitós, Elena, Mendoza, Rosa, Pintos‐Morell, Guillem, Albertazzi, Lorenzo, Rosell, Anna, Casas, Josefina, Villaverde, Antonio, Schwartz, Simó, Abasolo, Ibane
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953474/
https://ncbi.nlm.nih.gov/pubmed/33738082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12058
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados