Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44(+) tumor cells in culture, and upon lo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Pesarrodona, Mireia, Jauset, Toni, Díaz‐Riascos, Zamira V., Sánchez‐Chardi, Alejandro, Beaulieu, Marie‐Eve, Seras‐Franzoso, Joaquin, Sánchez‐García, Laura, Baltà‐Foix, Ricardo, Mancilla, Sandra, Fernández, Yolanda, Rinas, Ursula, Schwartz, Simó, Soucek, Laura, Villaverde, Antonio, Abasolo, Ibane, Vázquez, Esther
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Full Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755514/
https://ncbi.nlm.nih.gov/pubmed/31559131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900849
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge