Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44(+) tumor cells in culture, and upon lo...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Pesarrodona, Mireia, Jauset, Toni, Díaz‐Riascos, Zamira V., Sánchez‐Chardi, Alejandro, Beaulieu, Marie‐Eve, Seras‐Franzoso, Joaquin, Sánchez‐García, Laura, Baltà‐Foix, Ricardo, Mancilla, Sandra, Fernández, Yolanda, Rinas, Ursula, Schwartz, Simó, Soucek, Laura, Villaverde, Antonio, Abasolo, Ibane, Vázquez, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755514/
https://ncbi.nlm.nih.gov/pubmed/31559131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900849
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