Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44(+) tumor cells in culture, and upon lo...

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Vydáno v:Adv Sci (Weinh)
Hlavní autoři: Pesarrodona, Mireia, Jauset, Toni, Díaz‐Riascos, Zamira V., Sánchez‐Chardi, Alejandro, Beaulieu, Marie‐Eve, Seras‐Franzoso, Joaquin, Sánchez‐García, Laura, Baltà‐Foix, Ricardo, Mancilla, Sandra, Fernández, Yolanda, Rinas, Ursula, Schwartz, Simó, Soucek, Laura, Villaverde, Antonio, Abasolo, Ibane, Vázquez, Esther
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Full Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755514/
https://ncbi.nlm.nih.gov/pubmed/31559131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900849
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