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New Strategies for Enzyme Replacement Therapy for Lysosomal Storage Diseases

Enzyme replacement therapy is an established means of treating lysosomal storage diseases. Infused enzymes are normally targeted to the lysosomes of affected cells by interactions with cell-surface receptors that recognize carbohydrate moieties such as mannose and mannose 6-phosphate on the enzymes....

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Detalhes bibliográficos
Main Authors: Grubb, Jeffrey H., Vogler, Carole, Sly, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946059/
https://ncbi.nlm.nih.gov/pubmed/20345279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2009.0920
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