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Multiple Resistance at No Cost: Rifampicin and Streptomycin a Dangerous Liaison in the Spread of Antibiotic Resistance

Evidence is mounting that epistasis is widespread among mutations. The cost of carrying two deleterious mutations, or the advantage of acquiring two beneficial alleles, is typically lower that the sum of their individual effects. Much less is known on epistasis between beneficial and deleterious mut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Evol
Hauptverfasser: Durão, Paulo, Trindade, Sandra, Sousa, Ana, Gordo, Isabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576707/
https://ncbi.nlm.nih.gov/pubmed/26130082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv143
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