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DNA Breaks-Mediated Fitness Cost Reveals RNase HI as a New Target for Selectively Eliminating Antibiotic-Resistant Bacteria

Antibiotic resistance often generates defects in bacterial growth called fitness cost. Understanding the causes of this cost is of paramount importance, as it is one of the main determinants of the prevalence of resistances upon reducing antibiotics use. Here we show that the fitness costs of antibi...

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Publicat a:Mol Biol Evol
Autors principals: Balbontín, Roberto, Frazão, Nelson, Gordo, Isabel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321526/
https://ncbi.nlm.nih.gov/pubmed/33830249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msab093
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