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Multidrug-resistant bacteria compensate for the epistasis between resistances

Mutations conferring resistance to antibiotics are typically costly in the absence of the drug, but bacteria can reduce this cost by acquiring compensatory mutations. Thus, the rate of acquisition of compensatory mutations and their effects are key for the maintenance and dissemination of antibiotic...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Moura de Sousa, Jorge, Balbontín, Roberto, Durão, Paulo, Gordo, Isabel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395140/
https://ncbi.nlm.nih.gov/pubmed/28419091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001741
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