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Multiple Resistance at No Cost: Rifampicin and Streptomycin a Dangerous Liaison in the Spread of Antibiotic Resistance

Evidence is mounting that epistasis is widespread among mutations. The cost of carrying two deleterious mutations, or the advantage of acquiring two beneficial alleles, is typically lower that the sum of their individual effects. Much less is known on epistasis between beneficial and deleterious mut...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Durão, Paulo, Trindade, Sandra, Sousa, Ana, Gordo, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576707/
https://ncbi.nlm.nih.gov/pubmed/26130082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv143
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