An Antifungal Benzimidazole Derivative Inhibits Ergosterol Biosynthesis and Reveals Novel Sterols

Fungal infections are a leading cause of morbidity and death for hospitalized patients, mainly because they remain difficult to diagnose and to treat. Diseases range from widespread superficial infections such as vulvovaginal infections to life-threatening systemic candidiasis. For systemic mycoses,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Keller, Petra, Müller, Christoph, Engelhardt, Isabel, Hiller, Ekkehard, Lemuth, Karin, Eickhoff, Holger, Wiesmüller, Karl-Heinz, Burger-Kentischer, Anke, Bracher, Franz, Rupp, Steffen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576113/
https://ncbi.nlm.nih.gov/pubmed/26248360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00640-15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky