A Screening Assay Based on Host-Pathogen Interaction Models Identifies a Set of Novel Antifungal Benzimidazole Derivatives

Fungal infections are a serious health problem in clinics, especially in the immune-compromised patient. Disease ranges from widespread superficial infections like vulvovaginal infections to life-threatening systemic candidiasis. Especially for systemic mycoses, only a limited arsenal of antifungals...

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Main Authors: Burger-Kentischer, Anke, Finkelmeier, Doris, Keller, Petra, Bauer, Jörg, Eickhoff, Holger, Kleymann, Gerald, Abu Rayyan, Walid, Singh, Anurag, Schröppel, Klaus, Lemuth, Karin, Wiesmüller, Karl-Heinz, Rupp, Steffen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Chemistry; Biosynthesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186968/
https://ncbi.nlm.nih.gov/pubmed/21746957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01657-10
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