Načítá se...
Intrinsic differences in donor CD4 T cell IL-2 production influence severity of parent-into-F1 murine lupus by skewing the immune response either towards help for B cells and a sustained autoantibody response or towards help for CD8 T cells and a down regulatory Th1 response
Using the parent-into-F1 model of induced lupus and (C57Bl/6xDBA2) F1 mice as hosts, we compared the inherent lupus-inducing properties of the two parental strain CD4 T cells. To control for donor CD4 recognition of alloantigen, we used H-2(d) identical DBA/2 and B10.D2 donor T cells. We demonstrate...
Uloženo v:
| Vydáno v: | J Immunol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575913/ https://ncbi.nlm.nih.gov/pubmed/26320249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402782 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|