Intrinsic differences in donor CD4 T cell IL-2 production influence severity of parent-into-F1 murine lupus by skewing the immune response either towards help for B cells and a sustained autoantibody response or towards help for CD8 T cells and a down regulatory Th1 response

Ítems similars

• Both perforin and FasL are required for optimal CD8 T cell control of autoreactive B cells and autoantibody production in parent-into-F1 lupus mice(1)
  per: Soloviova, Kateryna, et al.
  Publicat: (2018)
• In vivo maturation of allo-specific CD8 CTL and prevention of lupus-like graft-vs.-host disease is critically dependent on T cell signaling through the TNF p75 receptor but not the TNF p55 receptor
  per: Soloviova, Kateryna, et al.
  Publicat: (2013)
• Enhancement of Suboptimal CD8 Cytotoxic T Cell Effector Function In Vivo Using Antigen-Specific CD80 Defective T Cells
  per: Puliaeva, Irina, et al.
  Publicat: (2010)
• Donor CD8 T Cells and IFN-γ Are Critical for Sex-Based Differences in Donor CD4 T Cell Engraftment and Lupus-Like Phenotype in Short-Term Chronic Graft-Versus-Host Disease Mice
  per: Foster, Anthony D., et al.
  Publicat: (2011)
• B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: feasibility and benefit.
  per: Soloviova, Kateryna, et al.
  Publicat: (2020)