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UPR(mt)-mediated cytoprotection and organismal aging

Time or age-dependent accumulation of mitochondrial damage and dysfunction is strongly associated with aging [1]. Thus, a major biomedical goal is to identify and therapeutically manipulate those inherent programs that protect against mitochondrial dysfunction to promote cell survival and organismal...

詳細記述

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書誌詳細
出版年:Biochim Biophys Acta
主要な著者: Schulz, Anna M., Haynes, Cole M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575829/
https://ncbi.nlm.nih.gov/pubmed/25857997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2015.03.008
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