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UPR(mt)-mediated cytoprotection and organismal aging

Time or age-dependent accumulation of mitochondrial damage and dysfunction is strongly associated with aging [1]. Thus, a major biomedical goal is to identify and therapeutically manipulate those inherent programs that protect against mitochondrial dysfunction to promote cell survival and organismal...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Schulz, Anna M., Haynes, Cole M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575829/
https://ncbi.nlm.nih.gov/pubmed/25857997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2015.03.008
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