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Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors

Infection of humans and chimpanzees with Hepatitis C virus (HCV) results in either the resolution of the acute infection or its progression to a persistent infection associated with chronic liver disease. In cohorts of human patients, resolution of HCV infection has been associated with homozygosity...

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Vydáno v:Immunogenetics
Hlavní autoři: Abi-Rached, Laurent, Guethlein, Lisbeth A., Norman, Paul J., Parham, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575274/
https://ncbi.nlm.nih.gov/pubmed/26260270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0863-0
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