Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser(315)

An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bacteria that are drug-tolerant; this might be becaus...

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Udgivet i:PLoS One
Main Authors: Jeeves, Rose E., Marriott, Alice A. N., Pullan, Steven T., Hatch, Kim A., Allnutt, Jon C., Freire-Martin, Irene, Hendon-Dunn, Charlotte L., Watson, Robert, Witney, Adam A., Tyler, Richard H., Arnold, Catherine, Marsh, Philip D., McHugh, Timothy D., Bacon, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575197/
https://ncbi.nlm.nih.gov/pubmed/26382066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138253
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