Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser(315)

An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. In any M. tuberculosis population there is a proportion of bacteria that are drug-tolerant; this might be becaus...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jeeves, Rose E., Marriott, Alice A. N., Pullan, Steven T., Hatch, Kim A., Allnutt, Jon C., Freire-Martin, Irene, Hendon-Dunn, Charlotte L., Watson, Robert, Witney, Adam A., Tyler, Richard H., Arnold, Catherine, Marsh, Philip D., McHugh, Timothy D., Bacon, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575197/
https://ncbi.nlm.nih.gov/pubmed/26382066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138253
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