Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

Alexander disease is a fatal neurodegenerative disease caused by mutations in the astrocyte intermediate filament glial fibrillary acidic protein (GFAP). The disease is characterized by elevated levels of GFAP and the formation of protein aggregates, known as Rosenthal fibers, within astrocytes. Lit...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: LaPash Daniels, Christine M., Paffenroth, Elizabeth, Austin, Elizabeth V., Glebov, Konstantin, Lewis, Diana, Walter, Jochen, Messing, Albee
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574949/
https://ncbi.nlm.nih.gov/pubmed/26378915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138132
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