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Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

Alexander disease is a fatal neurodegenerative disease caused by mutations in the astrocyte intermediate filament glial fibrillary acidic protein (GFAP). The disease is characterized by elevated levels of GFAP and the formation of protein aggregates, known as Rosenthal fibers, within astrocytes. Lit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: LaPash Daniels, Christine M., Paffenroth, Elizabeth, Austin, Elizabeth V., Glebov, Konstantin, Lewis, Diana, Walter, Jochen, Messing, Albee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574949/
https://ncbi.nlm.nih.gov/pubmed/26378915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138132
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