Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

To delineate specific developmental roles of transforming growth factor beta 1 (TGF-beta 1) we have disrupted its cognate gene in mouse embryonic stem cells by homologous recombination to generate TGF-beta 1 null mice. These mice do not produce detectable amounts of either TGF-beta 1 RNA or protein....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kulkarni, A B, Huh, C G, Becker, D, Geiser, A, Lyght, M, Flanders, K C, Roberts, A B, Sporn, M B, Ward, J M, Karlsson, S
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1993
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC45747/
https://ncbi.nlm.nih.gov/pubmed/8421714
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