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Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.

Aberrant expression of transforming growth factor beta 1 (TGF-beta 1) has been implicated in a number of disease processes, particularly those involving fibrotic and inflammatory lesions. To determine the in vivo effects of overexpression of TGF-beta 1 on the function and structure of hepatic as wel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sanderson, N, Factor, V, Nagy, P, Kopp, J, Kondaiah, P, Wakefield, L, Roberts, A B, Sporn, M B, Thorgeirsson, S S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708687/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2572
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