Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.

Aberrant expression of transforming growth factor beta 1 (TGF-beta 1) has been implicated in a number of disease processes, particularly those involving fibrotic and inflammatory lesions. To determine the in vivo effects of overexpression of TGF-beta 1 on the function and structure of hepatic as wel...

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Main Authors: Sanderson, N, Factor, V, Nagy, P, Kopp, J, Kondaiah, P, Wakefield, L, Roberts, A B, Sporn, M B, Thorgeirsson, S S
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC42260/
https://ncbi.nlm.nih.gov/pubmed/7708687
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