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Aiming for allosterism: Evaluation of allosteric modulators of CB(1) in a neuronal model

Cannabinoid pharmacology has proven nettlesome with issues of promiscuity a common theme among both agonists and antagonists. One recourse is to develop allosteric ligands to modulate cannabinoid receptor signaling. Cannabinoids have come late to the allosteric table. The ‘first-generation’ negative...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Straiker, Alex, Mitjavila, Jose, Yin, Danielle, Gibson, Anne, Mackie, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574285/
https://ncbi.nlm.nih.gov/pubmed/26211948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2015.07.017
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