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The CB(1) cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones

BACKGROUND AND PURPOSE: The cannabinoid CB(1) receptor is the chief mediator of the CNS effects of cannabinoids. In cell culture model systems, CB(1) receptors both desensitize and internalize on activation. Previous work suggests that the extreme carboxy-terminus of this receptor regulates internal...

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Main Authors: Straiker, Alex, Wager-Miller, Jim, Mackie, Ken
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423230/
https://ncbi.nlm.nih.gov/pubmed/22014214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01743.x
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