Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors

BACKGROUND: This study aims to further evaluate the specificity and selectivity of [(18)F]FTC-146 and obtain additional data to support its clinical translation. METHODS: The binding of [(19)F]FTC-146 to vesicular acetylcholine transporter (VAChT) was evaluated using [(3)H]vesamicol and PC12(A123.7)...

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Veröffentlicht in:EJNMMI Res
Hauptverfasser: Shen, Bin, James, Michelle L., Andrews, Lauren, Lau, Christopher, Chen, Stephanie, Palner, Mikael, Miao, Zheng, Arksey, Natasha C., Shuhendler, Adam J., Scatliffe, Shawn, Kaneshige, Kota, Parsons, Stanley M., McCurdy, Christopher R., Salehi, Ahmad, Gambhir, Sanjiv S., Chin, Frederick T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573970/
https://ncbi.nlm.nih.gov/pubmed/26384292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0122-2
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