Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors

BACKGROUND: This study aims to further evaluate the specificity and selectivity of [(18)F]FTC-146 and obtain additional data to support its clinical translation. METHODS: The binding of [(19)F]FTC-146 to vesicular acetylcholine transporter (VAChT) was evaluated using [(3)H]vesamicol and PC12(A123.7)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EJNMMI Res
Prif Awduron: Shen, Bin, James, Michelle L., Andrews, Lauren, Lau, Christopher, Chen, Stephanie, Palner, Mikael, Miao, Zheng, Arksey, Natasha C., Shuhendler, Adam J., Scatliffe, Shawn, Kaneshige, Kota, Parsons, Stanley M., McCurdy, Christopher R., Salehi, Ahmad, Gambhir, Sanjiv S., Chin, Frederick T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573970/
https://ncbi.nlm.nih.gov/pubmed/26384292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0122-2
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