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Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors

BACKGROUND: This study aims to further evaluate the specificity and selectivity of [(18)F]FTC-146 and obtain additional data to support its clinical translation. METHODS: The binding of [(19)F]FTC-146 to vesicular acetylcholine transporter (VAChT) was evaluated using [(3)H]vesamicol and PC12(A123.7)...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Shen, Bin, James, Michelle L., Andrews, Lauren, Lau, Christopher, Chen, Stephanie, Palner, Mikael, Miao, Zheng, Arksey, Natasha C., Shuhendler, Adam J., Scatliffe, Shawn, Kaneshige, Kota, Parsons, Stanley M., McCurdy, Christopher R., Salehi, Ahmad, Gambhir, Sanjiv S., Chin, Frederick T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573970/
https://ncbi.nlm.nih.gov/pubmed/26384292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0122-2
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