Genetic mapping uncovers cis-regulatory landscape of RNA editing

Adenosine-to-inosine (A-to-I) RNA editing, catalysed by ADAR enzymes conserved in metazoans, plays an important role in neurological functions. Although the fine-tuning mechanism provided by A-to-I RNA editing is important, the underlying rules governing ADAR substrate recognition are not well under...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ramaswami, Gokul, Deng, Patricia, Zhang, Rui, Anna Carbone, Mary, Mackay, Trudy F. C., Billy Li, Jin
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573499/
https://ncbi.nlm.nih.gov/pubmed/26373807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9194
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