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Identifying RNA editing sites using RNA sequencing data alone

We show that RNA editing sites can be called with high confidence using RNA sequencing data from multiple samples across either individuals or species, without the need for matched genomic DNA sequence. We identified many previously unidentified editing sites in both humans and Drosophila; our resul...

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Detalhes bibliográficos
Main Authors: Ramaswami, Gokul, Zhang, Rui, Piskol, Robert, Keegan, Liam P, Deng, Patricia, O'Connell, Mary A, Li, Jin Billy
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676881/
https://ncbi.nlm.nih.gov/pubmed/23291724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2330
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