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Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis
Adenosine-to-inosine (A-to-I) RNA editing catalyzed by ADAR enzymes occurs in double-stranded RNAs. Despite a compelling need towards predictive understanding of natural and engineered editing events, how the RNA sequence and structure determine the editing efficiency and specificity (i.e., cis-regu...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8041805/ https://ncbi.nlm.nih.gov/pubmed/33846332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22489-2 |
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