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Loss of ATRX suppresses resolution of telomere cohesion to control recombination in ALT cancer cells
The chromatin-remodeler ATRX is frequently lost in cancer cells that use ALT (alternative lengthening of telomeres) for telomere maintenance, but its function in telomere recombination is unknown. Here we show that loss of ATRX suppresses the timely resolution of sister telomere cohesion that normal...
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| Pubblicato in: | Cancer Cell |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573400/ https://ncbi.nlm.nih.gov/pubmed/26373281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.08.003 |
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