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Gastric Tumor-derived ANGPT2 Regulation by DARPP32 Promotes Angiogenesis

OBJECTIVE: Overexpression of dopamine and cAMP-regulated phosphoprotein, Mr 32000 (DARPP-32), and its truncated isoform (t-DARPP) are associated with gastric tumorigenesis. Herein, we investigated the role of DARPP-32 proteins in regulating angiopoietin 2 (ANGPT2) and promoting tumor angiogenesis. D...

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Publicat a:Gut
Autors principals: Chen, Zheng, Zhu, Shoumin, Hong, Jun, Soutto, Mohammed, Peng, DunFa, Belkhiri, Abbes, Xu, Zekuan, El-Rifai, Wael
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573388/
https://ncbi.nlm.nih.gov/pubmed/25779598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308416
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