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Design Parameters for Granzyme-Mediated Cytotoxic Lymphocyte Target-Cell Killing and Specificity

Cytotoxic lymphocytes are key elements of the immune system that are primarily responsible for targeting cells infected with intracellular pathogens, or cells that have become malignantly transformed. Target cells are killed mainly via lymphocyte exocytosis of specialized lysosomes containing perfor...

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Detaylı Bibliyografya
Yayımlandı:Biophys J
Asıl Yazarlar: Woodsworth, Daniel J., Dunsing, Valentin, Coombs, Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572491/
https://ncbi.nlm.nih.gov/pubmed/26244730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.045
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