Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage

Untreated HIV-1 infection leads to a slow decrease in CD4(+) T cell lymphocytes over time resulting in increased susceptibility to opportunistic infections (acquired immunodeficiency syndrome, AIDS) and ultimately death of the infected individual. Initially, the host’s immune response controls the i...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Saccon, Elisa, Mikaeloff, Flora, Figueras Ivern, Pol, Végvári, Ákos, Sönnerborg, Anders, Neogi, Ujjwal, van Domselaar, Robert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089382/
https://ncbi.nlm.nih.gov/pubmed/33953729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.669347
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