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Granzyme B; the chalk-mark of a cytotoxic lymphocyte

During cytotoxic lymphocyte (CL) mediated killing of target cells, granzyme B is released from the CL into the immune synapse. Recent studies have found that ELISPOT-detection of granzyme B correlated well with conventional assays for CL mediated killing. In this way, the released granzyme B can be...

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Detalhes bibliográficos
Main Authors: Waterhouse, Nigel J, Sedelies, Karin A, Clarke, Chris JP
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC528853/
https://ncbi.nlm.nih.gov/pubmed/15500699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-36
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