A General Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Target Cells

Cytotoxic T lymphocytes (CTLs) kill virus-infected cells and tumor cells, and play a critical role in immune protection. Our knowledge of how the CTL killing efficiency varies with CTL and target cell numbers is limited. Here, we simulate a region of lymphoid tissue using a cellular Potts model to c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gadhamsetty, Saikrishna, Marée, Athanasius F.M., Beltman, Joost B., de Boer, Rob J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2014
Pynciau:
Systems Biophysics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008826/
https://ncbi.nlm.nih.gov/pubmed/24739177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.048
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