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A General Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Target Cells
Cytotoxic T lymphocytes (CTLs) kill virus-infected cells and tumor cells, and play a critical role in immune protection. Our knowledge of how the CTL killing efficiency varies with CTL and target cell numbers is limited. Here, we simulate a region of lymphoid tissue using a cellular Potts model to c...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4008826/ https://ncbi.nlm.nih.gov/pubmed/24739177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.048 |
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