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Pendrin localizes to the adrenal medulla and modulates catecholamine release

Pendrin (Slc26a4) is a Cl(−)/HCO(3)(−) exchanger expressed in renal intercalated cells and mediates renal Cl(−) absorption. With pendrin gene ablation, blood pressure and vascular volume fall, which increases plasma renin concentration. However, serum aldosterone does not significantly increase in p...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Lazo-Fernandez, Yoskaly, Aguilera, Greti, Pham, Truyen D., Park, Annie Y., Beierwaltes, William H., Sutliff, Roy L., Verlander, Jill W., Pacak, Karel, Osunkoya, Adeboye O., Ellis, Carla L., Kim, Young Hee, Shipley, Gregory L., Wynne, Brandi M., Hoover, Robert S., Sen, Shurjo K., Plotsky, Paul M., Wall, Susan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572452/
https://ncbi.nlm.nih.gov/pubmed/26173457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00035.2015
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