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Pendrin localizes to the adrenal medulla and modulates catecholamine release

Pendrin (Slc26a4) is a Cl(−)/HCO(3)(−) exchanger expressed in renal intercalated cells and mediates renal Cl(−) absorption. With pendrin gene ablation, blood pressure and vascular volume fall, which increases plasma renin concentration. However, serum aldosterone does not significantly increase in p...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Lazo-Fernandez, Yoskaly, Aguilera, Greti, Pham, Truyen D., Park, Annie Y., Beierwaltes, William H., Sutliff, Roy L., Verlander, Jill W., Pacak, Karel, Osunkoya, Adeboye O., Ellis, Carla L., Kim, Young Hee, Shipley, Gregory L., Wynne, Brandi M., Hoover, Robert S., Sen, Shurjo K., Plotsky, Paul M., Wall, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572452/
https://ncbi.nlm.nih.gov/pubmed/26173457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00035.2015
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