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Pendrin localizes to the adrenal medulla and modulates catecholamine release

Pendrin (Slc26a4) is a Cl(−)/HCO(3)(−) exchanger expressed in renal intercalated cells and mediates renal Cl(−) absorption. With pendrin gene ablation, blood pressure and vascular volume fall, which increases plasma renin concentration. However, serum aldosterone does not significantly increase in p...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Lazo-Fernandez, Yoskaly, Aguilera, Greti, Pham, Truyen D., Park, Annie Y., Beierwaltes, William H., Sutliff, Roy L., Verlander, Jill W., Pacak, Karel, Osunkoya, Adeboye O., Ellis, Carla L., Kim, Young Hee, Shipley, Gregory L., Wynne, Brandi M., Hoover, Robert S., Sen, Shurjo K., Plotsky, Paul M., Wall, Susan M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572452/
https://ncbi.nlm.nih.gov/pubmed/26173457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00035.2015
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