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Pendrin gene ablation alters ENaC subcellular distribution and open probability

The present study explored whether the intercalated cell Cl(−)/HCO(3)(−) exchanger pendrin modulates epithelial Na(+) channel (ENaC) function by changing channel open probability and/or channel density. To do so, we measured ENaC subunit subcellular distribution by immunohistochemistry, single chann...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Main Authors: Pech, Vladimir, Wall, Susan M., Nanami, Masayoshi, Bao, Hui-Fang, Kim, Young Hee, Lazo-Fernandez, Yoskaly, Yue, Qiang, Pham, Truyen D., Eaton, Douglas C., Verlander, Jill W.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504930/
https://ncbi.nlm.nih.gov/pubmed/25972513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00564.2014
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