Deficient acid handling with distal RTA in the NBCe2 knockout mouse

In many circumstances, the pathogenesis of distal renal tubular acidosis (dRTA) is not understood. In the present study, we report that a mouse model lacking the electrogenic Na(+)-HCO(3)(−) cotransporter [NBCe2/Slc4a5; NBCe2 knockout (KO) mice] developed dRTA after an oral acid challenge. NBCe2 exp...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Renal Physiol
Egile Nagusiak: Wen, Donghai, Yuan, Yang, Cornelius, Ryan J., Li, Huaqing, Warner, Paige C., Wang, Bangchen, Wang-France, Jun, Boettger, Thomas, Sansom, Steven C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572397/
https://ncbi.nlm.nih.gov/pubmed/26109087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00163.2015
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