A carregar...
Increased ENaC activity contributes to hypertension caused by NBCe2 deficiency
The gene SLC4A5 encodes the Na(+)-HCO(3)(−) co-transporter electrogenic 2 (NBCe2), which is located in the distal nephron. Genetically deleting NBCe2 (KO) causes Na(+)-retention and hypertension, a phenotype that is diminished with alkali loading. We performed experiments with acid-loaded mice and d...
Na minha lista:
| Publicado no: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4465853/ https://ncbi.nlm.nih.gov/pubmed/25941340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05394 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|