Deficient acid handling with distal RTA in the NBCe2 knockout mouse

In many circumstances, the pathogenesis of distal renal tubular acidosis (dRTA) is not understood. In the present study, we report that a mouse model lacking the electrogenic Na(+)-HCO(3)(−) cotransporter [NBCe2/Slc4a5; NBCe2 knockout (KO) mice] developed dRTA after an oral acid challenge. NBCe2 exp...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Renal Physiol
Asıl Yazarlar: Wen, Donghai, Yuan, Yang, Cornelius, Ryan J., Li, Huaqing, Warner, Paige C., Wang, Bangchen, Wang-France, Jun, Boettger, Thomas, Sansom, Steven C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2015
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572397/
https://ncbi.nlm.nih.gov/pubmed/26109087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00163.2015
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