Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

Interpretation of biological mechanisms underlying genetic risk associations for prostate cancer is complicated by the relatively large number of risk variants (n = 100) and the thousands of surrogate SNPs in linkage disequilibrium. Here, we combined three distinct approaches: multiethnic fine-mappi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hum Mol Genet
Κύριοι συγγραφείς: Han, Ying, Hazelett, Dennis J., Wiklund, Fredrik, Schumacher, Fredrick R., Stram, Daniel O., Berndt, Sonja I., Wang, Zhaoming, Rand, Kristin A., Hoover, Robert N., Machiela, Mitchell J., Yeager, Merideth, Burdette, Laurie, Chung, Charles C., Hutchinson, Amy, Yu, Kai, Xu, Jianfeng, Travis, Ruth C., Key, Timothy J., Siddiq, Afshan, Canzian, Federico, Takahashi, Atsushi, Kubo, Michiaki, Stanford, Janet L., Kolb, Suzanne, Gapstur, Susan M., Diver, W. Ryan, Stevens, Victoria L., Strom, Sara S., Pettaway, Curtis A., Al Olama, Ali Amin, Kote-Jarai, Zsofia, Eeles, Rosalind A., Yeboah, Edward D., Tettey, Yao, Biritwum, Richard B., Adjei, Andrew A., Tay, Evelyn, Truelove, Ann, Niwa, Shelley, Chokkalingam, Anand P., Isaacs, William B., Chen, Constance, Lindstrom, Sara, Le Marchand, Loic, Giovannucci, Edward L., Pomerantz, Mark, Long, Henry, Li, Fugen, Ma, Jing, Stampfer, Meir, John, Esther M., Ingles, Sue A., Kittles, Rick A., Murphy, Adam B., Blot, William J., Signorello, Lisa B., Zheng, Wei, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie, Nemesure, Barbara, Carpten, John, Leske, M. Cristina, Wu, Suh-Yuh, Hennis, Anselm J. M., Rybicki, Benjamin A., Neslund-Dudas, Christine, Hsing, Ann W., Chu, Lisa, Goodman, Phyllis J., Klein, Eric A., Zheng, S. Lilly, Witte, John S., Casey, Graham, Riboli, Elio, Li, Qiyuan, Freedman, Matthew L., Hunter, David J., Gronberg, Henrik, Cook, Michael B., Nakagawa, Hidewaki, Kraft, Peter, Chanock, Stephen J., Easton, Douglas F., Henderson, Brian E., Coetzee, Gerhard A., Conti, David V., Haiman, Christopher A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2015
Θέματα:
Association Studies Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572069/
https://ncbi.nlm.nih.gov/pubmed/26162851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv269
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