The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein

Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distant site. Both experimental and theoretical evidence demonstrate that allostery can be communicated through altered slow relaxation protein dynamics without conformational change. The catabolite acti...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Townsend, Philip D., Rodgers, Thomas L., Glover, Laura C., Korhonen, Heidi J., Richards, Shane A., Colwell, Lucy J., Pohl, Ehmke, Wilson, Mark R., Hodgson, David R. W., McLeish, Tom C. B., Cann, Martin J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Computational Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571973/
https://ncbi.nlm.nih.gov/pubmed/26187469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669267
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