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Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart

AIMS: Notch1 signalling in the heart is mainly activated via expression of Jagged1 on the surface of cardiomyocytes. Notch controls cardiomyocyte proliferation and differentiation in the developing heart and regulates cardiac remodelling in the stressed adult heart. Besides canonical Notch receptor...

詳細記述

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書誌詳細
出版年:Cardiovasc Res
主要な著者: Metrich, Mélanie, Bezdek Pomey, April, Berthonneche, Corinne, Sarre, Alexandre, Nemir, Mohamed, Pedrazzini, Thierry
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571837/
https://ncbi.nlm.nih.gov/pubmed/26249804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvv209
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