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Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1

Notch signaling and blood flow regulate vascular formation and maturation, but how shear stress affects the different components of the Notch pathway in endothelial cells is poorly understood. We show that laminar shear stress results in a ligand specific gene expression profile in endothelial cells...

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Bibliografiske detaljer
Udgivet i:Integr Biol (Camb)
Main Authors: Driessen, R. C. H., Stassen, O. M. J. A., Sjöqvist, M., Suarez Rodriguez, F., Grolleman, J., Bouten, C. V. C., Sahlgren, C. M.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256362/
https://ncbi.nlm.nih.gov/pubmed/30328449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ib00036k
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