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Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1
Notch signaling and blood flow regulate vascular formation and maturation, but how shear stress affects the different components of the Notch pathway in endothelial cells is poorly understood. We show that laminar shear stress results in a ligand specific gene expression profile in endothelial cells...
Guardat en:
| Publicat a: | Integr Biol (Camb) |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6256362/ https://ncbi.nlm.nih.gov/pubmed/30328449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ib00036k |
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