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The Notch pathway controls fibrotic and regenerative repair in the adult heart
AIMS: In the adult heart, Notch signalling regulates the response to injury. Notch inhibition leads to increased cardiomyocyte apoptosis, and exacerbates the development of cardiac hypertrophy and fibrosis. The role of Notch in the mesenchymal stromal cell fraction, which contains cardiac fibroblast...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139705/ https://ncbi.nlm.nih.gov/pubmed/23166366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehs269 |
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