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DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis
[Image: see text] The promise of exploiting combinatorial synthesis for small molecule discovery remains unfulfilled due primarily to the “structure elucidation problem”: the back-end mass spectrometric analysis that significantly restricts one-bead-one-compound (OBOC) library complexity. The very m...
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| Pubblicato in: | ACS Comb Sci |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2015
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4571006/ https://ncbi.nlm.nih.gov/pubmed/26290177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.5b00106 |
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