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Two-stage biomarker panel study and estimation allowing early termination for futility
Technological advances have yielded a wealth of biomarkers that have the potential to detect chronic diseases such as cancer. However, most biomarkers considered for further validation turn out not to have strong enough performance to be used in clinical practice. Group sequential designs that allow...
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| Опубликовано в: : | Biostatistics |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570581/ https://ncbi.nlm.nih.gov/pubmed/25964662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxv017 |
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